Effect of transplantation of antibody heavy chain complementarity determining regions on ligand binding.
نویسندگان
چکیده
منابع مشابه
Effect of transplantation of antibody heavy chain complementarity determining regions on ligand binding.
Active site structure-function analyses of anti-fluorescein single chain antibody 4-4-20 and anti-single-stranded DNA single chain antibody 04-01 were conducted studying the ligand binding properties of hybrid antibodies resulting from systematic transplantation of heavy chain complementarity regions (HCDRs) from monoclonal antibody 4-4-20 into 04-01. Two prototype monoclonal antibodies were ch...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1994
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)51044-4